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Bioluminescent fish for environmental detection, drug testing, and hobby collectors
The Technology Researchers at the University of Tennessee have developed transgenic luminescent zebrafish. The gene cassette used to create the luminescence can be engineered to express exclusively in the presence of a particular compound or pollutant in the zebrafish’s environment, thus functioning as a bioluminescent environmental reporter. The...
Published: 6/10/2013
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Updated: 6/2/2013
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Inventor(s):
Gary Sayler
,
Michelle Connolly
,
Daniel Close
,
Steven Ripp
,
Theodore Henry
Keywords(s):
Animal Models
,
Diagnostics
,
Drug Discovery
,
Research Tools and Reagents
Category(s):
Engineering
,
Human Health
8MDP-Fluorescein: A Novel Equilibrative Nucleoside Transporter Probe probe
Reference: PD 12021-05 The Technology Nucleoside transporters are integral membrane glycoproteins that play critical roles in physiological nucleoside and nucleobase fluxes, and influence the efficacy of many nucleoside chemotherapy drugs. Fluorescent reporter ligands/substrates have been shown to be useful in the analysis of nucleoside transporter...
Published: 5/21/2013
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Updated: 5/21/2013
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Inventor(s):
John Buolamwini
,
Lin Wenwei
Keywords(s):
Fluorescent probe
,
Nucleoside transporter
,
Research Tools and Reagents
Category(s):
Research Tools
,
Human Health
A New Oxyma Derivative for Amide-forming Reactions in Water
Reference: PD 12110 Background In amide-forming reactions with R-amino acids, the use of a coupling additive such as benzotriazole derivatives (e.g., 1-hydroxy-7-azabenzotriazole (HOAt) and hydroxybenzotriazole (HOBt)) is essential to suppress racemization and improve the efficacy of peptide synthesis. Oxyma, ethyl 2-cyano-2-(hydroxyimino)acetate,...
Published: 6/4/2013
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Updated: 5/21/2013
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Inventor(s):
Michio Kurosu
,
Qinghui Wang
,
Yong Wang
Keywords(s):
Chemical reagent
,
Peptide synthesis
,
Peptides
,
Research Tools and Reagents
Category(s):
Research Tools
,
Chemistry & Materials