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A New Oxyma Derivative for Amide-forming Reactions in Water
Reference: PD 12110 Background In amide-forming reactions with R-amino acids, the use of a coupling additive such as benzotriazole derivatives (e.g., 1-hydroxy-7-azabenzotriazole (HOAt) and hydroxybenzotriazole (HOBt)) is essential to suppress racemization and improve the efficacy of peptide synthesis. Oxyma, ethyl 2-cyano-2-(hydroxyimino)acetate,...
Published: 6/4/2013   |   Updated: 5/21/2013   |   Inventor(s): Michio Kurosu, Qinghui Wang, Yong Wang
Keywords(s): Chemical reagent, Peptide synthesis, Peptides, Research Tools and Reagents
Category(s): Research Tools, Chemistry & Materials