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Novel heat stable protein ingredients for clear beverage products and delivery of bioactive compounds
The TechnologyResearchers at the University of Tennessee have discovered novel methods to stabilize whey proteins while simultaneously instilling transparency after thermal pasteurization and sterilization. The transparent property encourages marketability and shelf-life storage stability for popular clear food and beverage products. Thermo-stable proteins...
Published: 6/13/2013   |   Updated: 6/12/2013   |   Inventor(s): Qixin Zhong
Keywords(s):  
Category(s): Agriculture
Suppression of feline herpes virus replication by RNA interference with siRNAs
The Technology:Researchers at the University of Tennessee have discovered a novel method to suppress feline herpesvirus replication. In the United States at least 71% of cats are seropositive for feline herpesvirus. The symptoms may be severe and can persist throughout the cat’s life despite the availability of vaccines and treatment. Vaccines do not...
Published: 6/13/2013   |   Updated: 6/12/2013   |   Inventor(s): Rebecca Wilkes, Stephen Kania
Keywords(s):  
Category(s): Agriculture
Wood adhesives containing reinforced fillers for structural engineering products
Reference: 07054-01The TechnologyResearchers at the University of Tennessee have engineered high quality composite wood materials by incorporating the use of novel adhesives into the manufacturing processes. This innovation improves wood adhesive composition for various wood composite products, for example, oriented strand board (OSB), particleboard,...
Published: 6/13/2013   |   Updated: 6/12/2013   |   Inventor(s): Siqun Wang
Keywords(s):  
Category(s): Agriculture
Primary cilium-polycystin complex, a novel mechanosensing pathway in bone
Reference: PD 12083The Problem The skeleton adapts to alterations in mechanical loading by changing bone structure. Increased load results in increased bone mass as a result of increased osteoblast-mediated bone formation , whereas skeletal unloading, which occurs with immobilization, disuse, and exposure to low gravity, leads to low bone mass from...
Published: 6/13/2013   |   Updated: 6/12/2013   |   Inventor(s): Zhousheng Xiao, L. Darryl Quarles
Keywords(s): Therapeutics
Category(s): Human Health
Specific surface antigens of mycobacterium avium subsp. paratuberculosis and uses thereof
Reference: PD 04010-01The Technology The University of Tennessee have discovered a highly accurate method for diagnosing infectious diseases. This method improves accuracy (sensitivity) of diagnostic tests for Johne’s Disease from 30% to 95%. The method is also highly accurate when it comes to diagnosing another disease, bovine tuberculosis. Both of...
Published: 6/13/2013   |   Updated: 6/12/2013   |   Inventor(s): C. a. Speer, Shigetoshi Eda, Catherine Scott, Brad Elliott
Keywords(s):  
Category(s): Animal Health
Interferon gene signature for clinical use
Reference: PD 10023  The Problem Interferon (IFN) therapy, the conventional treatment for Hepatitis C (Hep C), presents with several drawbacks. These drawbacks include a long treatment trial to determine patient response to IFN, inefficiency in a significant number of patients, and significant side effects.  The response rate to IFN therapy is approximately...
Published: 6/13/2013   |   Updated: 6/12/2013   |   Inventor(s): Lawrence Pfeffer, Meiyun Fan, Charles Handorf, Susan Pfeffer
Keywords(s): Diagnostics, Infectious Diseases
Category(s): Human Health
Two monoclonal antibodies that specifically inhibit plasminogen activated induced by TPA
Reference: PD 13059  The Problem Although tissue plasminogen activator (TPA) is an effective therapy for ischemic stroke, it also causes severe and fatal bleeding in some patients.  Fear of bleeding and the lack of a specific antidote has led to widespread underuse of TPA by physicians. Serious bleeding occurs in 7-9% of ischemic stroke patients treated...
Published: 6/13/2013   |   Updated: 6/12/2013   |   Inventor(s): Guy Reed
Keywords(s): Biologics, Cardiovascular, Therapeutics
Category(s): Human Health
The two step neutralizing mouth wash to minimize the effects of acid erosion on tooth enamel.
Reference: PD13045The Problem Dental erosion is a significant oral health problem. It is exacerbated by highly acidic diets, certain medications causing low salivary flow, and systemic conditions such as gastroesophogeal reflux (GERD), and bulimia. Erosive tooth wear from hydrochloric acid occurs when stomach juice is regurgitated in conditions such...
Published: 6/13/2013   |   Updated: 6/11/2013   |   Inventor(s): Mojdeh Dehghan, Daranee VersluiS-Tanbirojn
Keywords(s): Dental product
Category(s): Human Health
The use of asialo-galactosylated triantennary oligosaccharides and their derivatives to support photoreceptor outer segment membrane assembly
Reference: PD06050The Problem Age-related Macular Degeneration (AMD) affects millions of people, progressively robbing them of their central vision and significantly reducing their quality of life. Without central vision, they are unable to read, recognize faces, drive, or perform countless daily activities. The vast majority of AMD cases consist of...
Published: 6/13/2013   |   Updated: 6/11/2013   |   Inventor(s): Monica Jablonski
Keywords(s): Ophthalmology, Therapeutics
Category(s): Human Health
Simple Optical Sensor for Biodiesel Contaminant in Jet Fuel
Reference: PD 13070-03The Problem: In April 2010, contamination in jet fuel caused the throttles of two engines on a Cathay Pacific flight to stick while in flight and nearly caused the lives of 322 passengers and crew on board.  Such incident is just one of the examples of the dangers posed by cross contamination in the fuel. FAME, or biodiesel, has...
Published: 6/13/2013   |   Updated: 6/11/2013   |   Inventor(s): Ziling (ben) Xue, Jonathan Fong
Keywords(s): BioFuels
Category(s): Chemistry & Materials
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