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Primary cilium-polycystin complex, a novel mechanosensing pathway in bone
Reference: PD 12083The Problem The skeleton adapts to alterations in mechanical loading by changing bone structure. Increased load results in increased bone mass as a result of increased osteoblast-mediated bone formation , whereas skeletal unloading, which occurs with immobilization, disuse, and exposure to low gravity, leads to low bone mass from...
Published: 6/13/2013
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Updated: 6/12/2013
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Inventor(s):
Zhousheng Xiao
,
L. Darryl Quarles
Keywords(s):
Therapeutics
Category(s):
Human Health